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| Hosokawa Alpine Milling Plant |
| STK-ID: 1403 Plant Built: 2000 Plant Shut Down: 2009 |
| Technology: Hosokawa Alpine |
| Capacity: 200kg/hr |
Description
1 off Milling Plant, designed by Hosokawa Alpine. The milling system is designed to mill up to 200kg/hr of pure dry drug powder using a proprietary air swept mill.In order to eliminate the explosion risk associated with milling organic material the mill system is filled with nitrogen and a purge system is used to maintain low oxygen and moisture content of the gas. The gas is also cooled in the circulation system to remove heat generated by the milling operation. |
More Details
A drum of product is emptied into a mobile drum charging isolator through a matcon discharge station on the top floor, a cone discharger at the base of the isolator discharges controlled slugs of powder in a highly controlled manner. The discharge station will feed powder directly into the screw feeder agitated hooper on the floor below. The feed screw will have varaible speed control to enable the product to be fed into the mill at a rate necessary to achieve a designated particle size. The product is then fed into a rotary valve which despenses the product into the nitrogen purged pin mill. From the mill the nitrogen and the product pass into a separation filter. The milled powder passes into a discharge hopper and a second rotary valve before being discharged into a drum filling booth and flowbox. The discharge flowbox incorporates a continious liner into 100 Litre kegs. The liner is loaded onto a cartridge outside the flowbox and manipulation of the cartridge and the liner is done inside the flowbox through glove ports. The nitrogen is recycled in a closed loop via a HEPA filter, Serpentine cooler and fan. Nitrogen is bled from the system and make up nitrogen is controlled by sized restricted orifce plates. |
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